FDA wants to know what you know about Per- and Polyfluoroalkyl Substances (PFAS) in seafood

The U.S. Food and Drug Administration has issued a request for information on per- and polyfluoroalkyl substances (PFAS) in seafood. The FDA is seeking scientific data and information from the seafood industry, academia, state, and federal agencies, as well as other interested entities, on PFAS concentrations in seafood, the surrounding environment, and processing water, as well as mitigation strategies for reducing exposure to PFAS in seafood.

“This request is part of our continued work to increase our understanding of the potential for PFAS exposure from seafood and to reduce dietary exposure to PFAS that may pose a health concern,” according to a statement from the FDA.

The FDA collects samples and tests for PFAS in the general food supply in several ways, including the FDA’s Total Diet Study (TDS), which has been in use since 2019. Testing indicates that seafood may be at higher risk for environmental PFAS contamination than other foods. In 2021 and 2022, to expand on the results from the TDS samples and evaluate potential exposure to PFAS from other seafood types, the FDA collected additional seafood samples and conducted surveys targeting the most commonly consumed seafood in the United States. However, the data on PFAS in seafood are still limited for many other seafood types.

Addressing the potential effects of Americans’ PFAS exposure is a national priority and is coordinated across several federal agencies. Through these interagency collaborations, the FDA is working to identify routes of PFAS exposure, understand associated health risks, and reduce the public’s dietary exposure to PFAS that may pose health concerns. The FDA reports it is committed to maintaining the availability of safe seafood, as it provides key nutrients for children and adults.

The agency will continue to apply the latest science to increase its understanding of the levels of PFAS in seafood and the reasons for differences within and across types of seafood. It will also help identify strategies that can reduce PFAS in seafood. FDA’s request for information is an opportunity for interested entities to help address the existing data gaps, advance the agency’s public health mission, and further support the Administration’s comprehensive approach to addressing PFAS and advancing clean air, water, and food.

To ensure comments regarding “Per- and Polyfluoroalkyl Substances (PFAS) in Seafood; Request for Information” are considered, written and electronic comments should be submitted by Feb. 18, 2025.

Submit comments electronically on Regulations.gov to docket number FDA-2024-N-4604.

Submit written/paper submissions to:
Dockets Management Staff (HFA-305)
Food and Drug Administration
5630 Fishers Lane, Rm 1061
Rockville, MD 20852

All submissions received must include the Docket No. FDA-2024-N-4604 for “Per- and Polyfluoroalkyl Substances (PFAS) in Seafood; Request for Information.”

Additional Information

• Federal Register Notice
• FDA Per-and Polyfluoroalkyl Substances (PFAS)
• FDA Shares Results on PFAS Testing in Seafood

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